个人简介
博士生导师，电子科技大学、四川省人民医院健康管理研究所/健康管理中心教授。主要研究免疫与代谢两个系统的相互调控机制及病理意义，特别是阐明了丝氨酸/甘氨酸/一碳代谢（Serine/Glycine/One Carbon，SGOC）网络动态调控巨噬细胞功能从而影响病毒感染性疾病与肿瘤发生发展的重要作用。作为主要作者（通讯/第一）在Cell Metab.、Nat Cell Biol.、Cell Rep.等期刊发表10篇研究性论文，影响因子累计134，平均影响因子15，单篇最高影响因子31.4（最后通讯作者），单篇最高他引150次。多篇论文受到学术界关注，包括Cell Metab.同期专题评述（2021），被Nat Cell Biol.、Nature Reviews、Cell Metab.等期刊上发表的本领域重量级综述引用和评价。作为课题组独立PI以来已获得3项国家自然科学基金面上项目和多项地方基金项目资助。兼任“中国生物化学与分子生物学会代谢专业分会委员”、“中国生物物理学会代谢生物学分会青年理事”等学术职务。入选天津市“131”创新型人才（2018）、天津市“中青年骨干创新人才培养计划”（2019）、天津医科大学“科技创新先进个人”（2021）和电子科技大学“百人计划”（2023）。
教育经历
暂无公开信息
科研项目
- 代谢酶 MTHFD2在巨噬细胞极化和肿瘤发展中的作用及机制研究, 国家自然科学基金面上项目
- SUCLA2在解酮代谢和肿瘤发展中的作用及机制研究, 国家自然科学基金面上项目
- PGK1在肿瘤自噬中的作用及机制研究, 国家自然科学基金面上项目
- 丝氨酸代谢抑制抗病毒天然免疫的机制研究, 天津市自然科学基金面上项目
论文／期刊
- Yan Cui, Zihan Li, Lina Ni, Sujun Yu, Xiao Shan Penghui Hu, Zemin Ji, Weijia Jing, Yanzhao Zhou, Baochen Wang, Hongyuan Dong, and Jinxue Zhou, Keliang Xie, Qiujing Yu, Induction of MTHFD2 in Macrophages Inhibits Reactive Oxygen Species-mediated NF-κB Activation and Protects against Inflammatory Responses., Journal of immunology ,
- Man Shang, Lina Ni, Xiao Shan, Yan Cui, Penghui Hu, Zemin Ji, Long Shen, Yanan Zhang, Jinxue Zhou, Bing Chen, Ting Wang, and Qiujing Yu, MTHFD2 reprograms macrophage polarization by inhibiting PTEN., Cell Report ,
- Xiao Shan, Penghui Hu, Lina Ni, Long Shen, Yanan Zhang, Zemin Ji, Yan Cui, Meihua Guo, Haoan Wang, Liyuan Ran, Kun Yang, Ting Wang, Lei Wang, Bin Chen, Zhi Yao, Yingjie Wu, and Qiujing Yu, Serine Metabolism Orchestrates Macrophage Polarization by Regulating the IGF1–p38 Axis., Cellular and molecular immunology ,
- Long Shen, Penghui Hu, Yanan Zhang, Zemin Ji, Xiao Shan, Lina Ni, Na Ning, Jing Wang, He Tian, Guanghou Shui, Yukang Yuan, Guoli Li, Hui Zheng, Xiang-Ping Yang, Dandan Huang, Xiangling Feng, Mulin Jun Li, Zhe Liu, Ting Wang, and Qiujing Yu, Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation., Cell metabolism ,
- Man Shang, Huijie Yang, Ran Yang, Tao Chen, Yuan Fu, Yeyi Li, Xianlong Fang, Kangjian Zhang, Jianju Zhang, Hui Li, Xueping Cao, Jinfa Gu, Jianwen Xiao, Qi Zhang, Xinyuan Liu, and Qiujing Yu, Ting Wang, The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation., Nature communications ,
- Ting Wang, Qiujing Yu, Jingjie Li, Bin Hu, Qin Zhao, Chunmin Ma, Wenhua Huang, Lingang Zhuo, Houqin Fang, Lujian Liao, Y Eugene Chin, and Yuhui Jiang, O-GlcNAcylation of fumarase maintains tumor growth under glucose deficiency., Nature cell biology ,
- Qiujing Yu, Bin Zhao, Jun Gui, Kanstantsin V. Katlinski, Angela Brice, Yan Gao, ChangHong Li, Jake A. Kushner, Constantinos Koumenis, J. Alan Diehl, and Serge Y. Fuchs, Type I interferons mediate pancreatic toxicities of PERK inhibition., Proceedings of the National Academy of Sciences of the United States of America ,
- Qiujing Yu, Yuliya V Katlinskaya and Christopher J Carbone, Bin Zhao, Kanstantsin V Katlinski, Hui Zheng, Manti Guha, Ning Li, Qijun Chen, Ting Yang, Christopher J Lengner, Roger A Greenberg, F Brad Johnson, Serge Y Fuchs, Lengner CJ, Greenberg RA, Johnson FB, Fuchs SY*. DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function., Cell reports ,
- Qiujing Yu, Christopher J Carbone, Yuliya V Katlinskaya, Hui Zheng, Ke Zheng, Mengcheng Luo, P Jeremy Wang, Roger A Greenberg, and Serge Y Fuchs, Type I interferon controls propagation of long interspersed element-1., The Journal of biological chemistry ,